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Skindermlab formulation laboratory

Ingredient Glossary

Find the active ingredients behind our formulations, what they do, and how they differ from one another — all on one page.

Regenerative & Biostimulators

2026's fastest-growing aesthetic trend: ingredients that trigger the skin's own repair capacity instead of "reshaping" it.

PDRN (Polydeoxyribonucleotide)

Low-molecular-weight DNA fragments derived from salmon. Activates the adenosine A2A receptor to support tissue repair and micro-circulation — the polynucleotide category's ingredient with the deepest clinical track record.

Read what PDRN is →

PN (Polynucleotide)

A longer-chain nucleotide structure than PDRN; forms a gel-like network under the skin, making it stronger for volumizing and hydration. Often positioned as a complementary protocol alongside PDRN.

Read about PN under the eyes →

Exosome

Cell-derived vesicle structures that mediate cell-to-cell communication. Trigger regeneration signals to support tissue renewal; also widely used in post-laser care in Korean medical spas.

Read about exosome technology →

PLLA (Poly-L-Lactic Acid)

A biodegradable synthetic polymer that stimulates fibroblasts to build new collagen over months. The pioneer of the biostimulator category for gradual, long-lasting firming results.

Read the biostimulator trend →

PCL (Polycaprolactone)

A slow-dissolving, biodegradable polymer that delivers long-acting collagen stimulation, offering longer-lasting mechanical support and stimulation compared to PLLA.

Read the biostimulator trend →

CaHA (Calcium Hydroxylapatite)

A dual-action biostimulator raw material that delivers both immediate volume and gradual collagen stimulation over time — known for its bone-mineral-like, biocompatible structure.

Read the biostimulator trend →

Peptides (Biomimetic Peptides)

Short amino acid chains that mimic the skin's own signaling molecules to trigger collagen/elastin production or barrier repair. Widely used in topical serum and cream formulations.

Read about biomimetic peptides →

Salmon DNA

The source material behind PDRN and polynucleotide-based products — low-molecular-weight DNA fragments with high compatibility with human DNA.

Read where PDRN comes from →

Hydration & Barrier

Classic actives that strengthen the skin's water-holding capacity and protective barrier, with the most consistent results.

Ceramides

One of the skin barrier's natural building blocks; prevents moisture loss and protects against external stressors. The foundation of barrier-repair cream and serum formulations.

Read the signs of ceramide deficiency →

Snail Mucin

A natural secretion containing glycoproteins, hyaluronic acid, and allantoin; known for its repairing and hydrating properties, a K-beauty formulation staple.

Read about snail mucin →

Centella / Cica

An active derived from Centella Asiatica known for its soothing, repairing effect; preferred in formulations for sensitive and reactive skin.

Read why centella is in every routine →

Non-Cross-Linked HA

Non-cross-linked, low-molecular-weight hyaluronic acid used for topical/mesotherapy-assisted hydration rather than injectable filling — absorbs quickly.

Read about non-injectable hyaluronic acid →

Brightening & Repair

The active group targeting uneven tone, dullness, and early signs of aging.

Niacinamide

A vitamin B3 derivative that reduces uneven tone, improves the appearance of pores, and supports barrier function — a broadly tolerated active compatible with nearly every skin type.

Read the niacinamide vs Vitamin C comparison →

Retinol

A vitamin A derivative that accelerates cell turnover and reduces the appearance of fine lines and pores. The reference active of classic anti-aging formulations.

Read the common retinol mistakes to avoid →

Vitamin C

A potent antioxidant that brightens, supports collagen synthesis, and protects against environmental stress; typically favored in morning routines.

Read the niacinamide vs Vitamin C comparison →

Glutathione

A powerful antioxidant the body produces naturally; used in formulations aimed at regulating melanin production to brighten and even out skin tone.

Read about glutathione for skin brightening →

Propolis

A natural active produced by bees, known for its antibacterial and repairing properties; featured in formulations for barrier support and soothing.

Read why propolis works for acne-prone skin →

Hair Care

The strengthening active group targeted at the hair follicle and scalp.

Caffeine

An active widely used in hair mesotherapy formulations that supports the hair follicle by boosting micro-circulation.

Read about caffeine for hair loss →

Vitamin Complex (Hair)

A cocktail formulation combining B-group vitamins and supporting actives to nourish the hair follicle.

Read the vitamin complex vs caffeine comparison →

Can't find the active you're looking for?

Our portfolio keeps growing — get in touch for a custom active or formulation request.